Description of the Modified Semi-Micro Plaque Reduction Neutralization Test for Dengue Virus

  • Yamarte Martínez,Patricia Essayag ,Peggy García


In most laboratories dengue antibodies are measured by hemagglutination inhibition (HI), complement fixation (CF), or enzyme-linked immunoassay (ELISA) tests adapted to micromethods. They do not reliably identify the infecting serotype. This paper proposes a description of the modified semi-micro plaque reduction neutralization test used successfully